This gene encodes a member of the ASPP (apoptosis-stimulating protein of p53) family of p53 interacting proteins. The protein contains four ankyrin repeats and an SH3 domain involved in protein-protein interactions. ASPP proteins are required for the induction of apoptosis by p53-family proteins. They promote DNA binding and transactivation of p53-family proteins on the promoters of proapoptotic genes. Expression of this gene is regulated by the E2F transcription factor. [provided by RefSeq, Jul 2008]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| PPP1R13B-20-RE | 20 (40 μL) | 200 μL |  |
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| PPP1R13B-20-OR | 20 (40 μL) | 200 μL |  |
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| PPP1R13B-20-GO | 20 (40 μL) | 200 μL |  |
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| PPP1R13B-20-GR | 20 (40 μL) | 200 μL |  |
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| PPP1R13B-20-AQ | 20 (40 μL) | 200 μL |  |
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This gene encodes a member of the ASPP (apoptosis-stimulating protein of p53) family of p53 interacting proteins. The protein contains four ankyrin repeats and an SH3 domain involved in protein-protein interactions. ASPP proteins are required for the induction of apoptosis by p53-family proteins. They promote DNA binding and transactivation of p53-family proteins on the promoters of proapoptotic genes. Expression of this gene is regulated by the E2F transcription factor. [provided by RefSeq, Jul 2008]
Gene Symbol : PPP1R13B
Gene Name : Protein phosphatase 1 regulatory subunit 13B
Chromosome : CHR 14: 103,848,966-103,733,750
Locus : 14q32.33
Alt. Genes : HIPK3
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