PPHLN1 FISH Probe

The protein encoded by this gene is one of the several proteins that become sequentially incorporated into the cornified cell envelope during the terminal differentiation of keratinocyte at the outer layers of epidermis. This protein interacts with periplakin, which is known as a precursor of the cornified cell envelope. The cellular localization pattern and insolubility of this protein suggest that it may play a role in epithelial differentiation and contribute to epidermal integrity and barrier formation. Multiple alternatively spliced transcript variants encoding distinct isoforms have been observed. [provided by RefSeq, Jul 2008]


Gene Details
SKU Test Kits Buffer Dye Color Order Now
PPHLN1-20-RE 20 (40 μL) 200 μL color Request Pricing
PPHLN1-20-OR 20 (40 μL) 200 μL color Request Pricing
PPHLN1-20-GO 20 (40 μL) 200 μL color Request Pricing
PPHLN1-20-GR 20 (40 μL) 200 μL color Request Pricing
PPHLN1-20-AQ 20 (40 μL) 200 μL color Request Pricing

Gene Summary

The protein encoded by this gene is one of the several proteins that become sequentially incorporated into the cornified cell envelope during the terminal differentiation of keratinocyte at the outer layers of epidermis. This protein interacts with periplakin, which is known as a precursor of the cornified cell envelope. The cellular localization pattern and insolubility of this protein suggest that it may play a role in epithelial differentiation and contribute to epidermal integrity and barrier formation. Multiple alternatively spliced transcript variants encoding distinct isoforms have been observed. [provided by RefSeq, Jul 2008]

Gene Details

Gene Symbol : PPHLN1

Gene Name : Periphilin 1

Chromosome : CHR 12: 423,261,25-424,486,20

Locus : 12q12

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