This gene encodes the second largest subunit of RNA polymerase III, the polymerase responsible for synthesizing transfer and small ribosomal RNAs in eukaryotes. The largest subunit and the encoded protein form the catalytic center of RNA polymerase III. Mutations in this gene are a cause of hypomyelinating leukodystrophy. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Dec 2011]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| POLR3B-20-RE | 20 (40 μL) | 200 μL |  |
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| POLR3B-20-OR | 20 (40 μL) | 200 μL |  |
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| POLR3B-20-GO | 20 (40 μL) | 200 μL |  |
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| POLR3B-20-GR | 20 (40 μL) | 200 μL |  |
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| POLR3B-20-AQ | 20 (40 μL) | 200 μL |  |
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This gene encodes the second largest subunit of RNA polymerase III, the polymerase responsible for synthesizing transfer and small ribosomal RNAs in eukaryotes. The largest subunit and the encoded protein form the catalytic center of RNA polymerase III. Mutations in this gene are a cause of hypomyelinating leukodystrophy. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Dec 2011]
Gene Symbol : POLR3B
Gene Name : RNA polymerase III subunit B
Chromosome : CHR 12: 106,357,657-106,510,197
Locus : 12q23.3
Alt. Genes : HIPK3
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