This gene encodes a transmembrane proteolipid protein that is the predominant component of myelin. The encoded protein may play a role in the compaction, stabilization, and maintenance of myelin sheaths, as well as in oligodendrocyte development and axonal survival. Mutations in this gene cause Pelizaeus-Merzbacher disease and spastic paraplegia type 2. Alternatively splicing results in multiple transcript variants, including the DM20 splice variant. [provided by RefSeq, Feb 2015]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| PLP1-20-RE | 20 (40 μL) | 200 μL |  |
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| PLP1-20-OR | 20 (40 μL) | 200 μL |  |
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| PLP1-20-GO | 20 (40 μL) | 200 μL |  |
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| PLP1-20-GR | 20 (40 μL) | 200 μL |  |
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| PLP1-20-AQ | 20 (40 μL) | 200 μL |  |
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This gene encodes a transmembrane proteolipid protein that is the predominant component of myelin. The encoded protein may play a role in the compaction, stabilization, and maintenance of myelin sheaths, as well as in oligodendrocyte development and axonal survival. Mutations in this gene cause Pelizaeus-Merzbacher disease and spastic paraplegia type 2. Alternatively splicing results in multiple transcript variants, including the DM20 splice variant. [provided by RefSeq, Feb 2015]
Gene Symbol : PLP1
Gene Name : Proteolipid protein 1
Chromosome : CHR X: 103,776,505-103,792,618
Locus : Xq22.2
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