This gene encodes a pleckstrin homology domain-containing adapter protein. The encoded protein is localized to the plasma membrane where it specifically binds phosphatidylinositol 3,4-bisphosphate. This protein may be involved in the formation of signaling complexes in the plasma membrane. Polymorphisms in this gene are associated with age-related macular degeneration. Alternate splicing results in multiple transcript variants. A pseudogene of this gene is found on chromosome 5.[provided by RefSeq, Sep 2010]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| PLEKHA1-20-RE | 20 (40 μL) | 200 μL |  |
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| PLEKHA1-20-OR | 20 (40 μL) | 200 μL |  |
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| PLEKHA1-20-GO | 20 (40 μL) | 200 μL |  |
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| PLEKHA1-20-GR | 20 (40 μL) | 200 μL |  |
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| PLEKHA1-20-AQ | 20 (40 μL) | 200 μL |  |
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This gene encodes a pleckstrin homology domain-containing adapter protein. The encoded protein is localized to the plasma membrane where it specifically binds phosphatidylinositol 3,4-bisphosphate. This protein may be involved in the formation of signaling complexes in the plasma membrane. Polymorphisms in this gene are associated with age-related macular degeneration. Alternate splicing results in multiple transcript variants. A pseudogene of this gene is found on chromosome 5.[provided by RefSeq, Sep 2010]
Gene Symbol : PLEKHA1
Gene Name : Pleckstrin homology domain containing A1
Chromosome : CHR 10: 122,374,577-122,432,354
Locus : 10q26.13
Alt. Genes : DNAL4
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