This gene encodes a member of the polycystin protein family. The encoded protein is a multi-pass membrane protein that functions as a calcium permeable cation channel, and is involved in calcium transport and calcium signaling in renal epithelial cells. This protein interacts with polycystin 1, and they may be partners in a common signaling cascade involved in tubular morphogenesis. Mutations in this gene are associated with autosomal dominant polycystic kidney disease type 2. [provided by RefSeq, Mar 2011]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| PKD2-20-RE | 20 (40 μL) | 200 μL |  |
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| PKD2-20-OR | 20 (40 μL) | 200 μL |  |
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| PKD2-20-GO | 20 (40 μL) | 200 μL |  |
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| PKD2-20-GR | 20 (40 μL) | 200 μL |  |
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| PKD2-20-AQ | 20 (40 μL) | 200 μL |  |
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This gene encodes a member of the polycystin protein family. The encoded protein is a multi-pass membrane protein that functions as a calcium permeable cation channel, and is involved in calcium transport and calcium signaling in renal epithelial cells. This protein interacts with polycystin 1, and they may be partners in a common signaling cascade involved in tubular morphogenesis. Mutations in this gene are associated with autosomal dominant polycystic kidney disease type 2. [provided by RefSeq, Mar 2011]
Gene Symbol : PKD2
Gene Name : Polycystin 2, transient receptor potential cation channel
Chromosome : CHR 4: 880,076,46-880,777,78
Locus : 4q22.1
Alt. Genes : DNAL4
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