This gene encodes a member of the prefoldin alpha subunit family. The encoded protein is one of six subunits of prefoldin, a molecular chaperone complex that binds and stabilizes newly synthesized polypeptides, thereby allowing them to fold correctly. The complex, consisting of two alpha and four beta subunits, forms a double beta barrel assembly with six protruding coiled-coils. The encoded protein may also repress the transcriptional activity of the proto-oncogene c-Myc. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Jul 2008]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| PFDN5-20-RE | 20 (40 μL) | 200 μL |  |
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| PFDN5-20-OR | 20 (40 μL) | 200 μL |  |
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| PFDN5-20-GO | 20 (40 μL) | 200 μL |  |
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| PFDN5-20-GR | 20 (40 μL) | 200 μL |  |
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| PFDN5-20-AQ | 20 (40 μL) | 200 μL |  |
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This gene encodes a member of the prefoldin alpha subunit family. The encoded protein is one of six subunits of prefoldin, a molecular chaperone complex that binds and stabilizes newly synthesized polypeptides, thereby allowing them to fold correctly. The complex, consisting of two alpha and four beta subunits, forms a double beta barrel assembly with six protruding coiled-coils. The encoded protein may also repress the transcriptional activity of the proto-oncogene c-Myc. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Jul 2008]
Gene Symbol : PFDN5
Gene Name : Prefoldin subunit 5
Chromosome : CHR 12: 532,954,50-532,994,49
Locus : 12q13.13
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