This gene is a member of the Period family of genes and is expressed in a circadian pattern in the suprachiasmatic nucleus, the primary circadian pacemaker in the mammalian brain. Genes in this family encode components of the circadian rhythms of locomotor activity, metabolism, and behavior. This gene is upregulated by CLOCK/ARNTL heterodimers but then represses this upregulation in a feedback loop using PER/CRY heterodimers to interact with CLOCK/ARNTL. Polymorphisms in this gene have been linked to sleep disorders. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2014]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| PER3-20-RE | 20 (40 μL) | 200 μL |  |
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| PER3-20-OR | 20 (40 μL) | 200 μL |  |
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| PER3-20-GO | 20 (40 μL) | 200 μL |  |
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| PER3-20-GR | 20 (40 μL) | 200 μL |  |
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| PER3-20-AQ | 20 (40 μL) | 200 μL |  |
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This gene is a member of the Period family of genes and is expressed in a circadian pattern in the suprachiasmatic nucleus, the primary circadian pacemaker in the mammalian brain. Genes in this family encode components of the circadian rhythms of locomotor activity, metabolism, and behavior. This gene is upregulated by CLOCK/ARNTL heterodimers but then represses this upregulation in a feedback loop using PER/CRY heterodimers to interact with CLOCK/ARNTL. Polymorphisms in this gene have been linked to sleep disorders. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2014]
Gene Symbol : PER3
Gene Name : Period circadian regulator 3
Chromosome : CHR 1: 778,428,4-784,518,0
Locus : 1p36.23
Alt. Genes : FARP1
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