This gene encodes a member of the pyruvate dehydrogenase kinase family. The encoded protein phosphorylates pyruvate dehydrogenase, down-regulating the activity of the mitochondrial pyruvate dehydrogenase complex. Overexpression of this gene may play a role in both cancer and diabetes. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Dec 2010]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| PDK2-20-RE | 20 (40 μL) | 200 μL |  |
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| PDK2-20-OR | 20 (40 μL) | 200 μL |  |
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| PDK2-20-GO | 20 (40 μL) | 200 μL |  |
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| PDK2-20-GR | 20 (40 μL) | 200 μL |  |
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| PDK2-20-AQ | 20 (40 μL) | 200 μL |  |
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This gene encodes a member of the pyruvate dehydrogenase kinase family. The encoded protein phosphorylates pyruvate dehydrogenase, down-regulating the activity of the mitochondrial pyruvate dehydrogenase complex. Overexpression of this gene may play a role in both cancer and diabetes. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Dec 2010]
Gene Symbol : PDK2
Gene Name : Pyruvate dehydrogenase kinase 2
Chromosome : CHR 17: 500,947,36-501,113,68
Locus : 17q21.33
Alt. Genes : PLXNC1
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