This gene encodes a member of the disulfide isomerase (PDI) family of endoplasmic reticulum (ER) proteins that catalyze protein folding and thiol-disulfide interchange reactions. The encoded protein has an N-terminal ER-signal sequence, three catalytically active thioredoxin (TRX) domains, a TRX-like domain, and a C-terminal ER-retention sequence. The N-terminal TRX-like domain is the primary binding site for the major ER chaperone calreticulin and possibly other proteins and substrates as well. Alternative splicing results in multiple protein- and non-protein-coding transcript variants. [provided by RefSeq, Dec 2016]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| PDIA5-20-RE | 20 (40 μL) | 200 μL |  |
Request Pricing |
| PDIA5-20-OR | 20 (40 μL) | 200 μL |  |
Request Pricing |
| PDIA5-20-GO | 20 (40 μL) | 200 μL |  |
Request Pricing |
| PDIA5-20-GR | 20 (40 μL) | 200 μL |  |
Request Pricing |
| PDIA5-20-AQ | 20 (40 μL) | 200 μL |  |
Request Pricing |
This gene encodes a member of the disulfide isomerase (PDI) family of endoplasmic reticulum (ER) proteins that catalyze protein folding and thiol-disulfide interchange reactions. The encoded protein has an N-terminal ER-signal sequence, three catalytically active thioredoxin (TRX) domains, a TRX-like domain, and a C-terminal ER-retention sequence. The N-terminal TRX-like domain is the primary binding site for the major ER chaperone calreticulin and possibly other proteins and substrates as well. Alternative splicing results in multiple protein- and non-protein-coding transcript variants. [provided by RefSeq, Dec 2016]
Gene Symbol : PDIA5
Gene Name : Protein disulfide isomerase family A member 5
Chromosome : CHR 3: 123,067,008-123,162,105
Locus : 3q21.1
Alt. Genes : HIPK3
Lorem Ipsum is simply dummy text of the printing and typesetting industry.
Lorem Ipsum is simply dummy text of the printing and typesetting industry.