This gene encodes an enzyme that belongs to the 3'5'-cyclic nucleotide phosphodiesterase family. Members of this family catalyze hydrolysis of the cyclic nucleotides, cyclic adenosine monophosphate and cyclic guanosine monophosphate, to the corresponding nucleoside 5'-monophosphates. The enzyme encoded by this gene regulates proliferation and migration of vascular smooth muscle cells, and neointimal hyperplasia. This enzyme also plays a role in pathological vascular remodeling by regulating the stability of growth factor receptors, such as PDGF-receptor-beta. [provided by RefSeq, Jul 2016]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| PDE1C-20-RE | 20 (40 μL) | 200 μL |  |
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| PDE1C-20-OR | 20 (40 μL) | 200 μL |  |
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| PDE1C-20-GO | 20 (40 μL) | 200 μL |  |
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| PDE1C-20-GR | 20 (40 μL) | 200 μL |  |
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| PDE1C-20-AQ | 20 (40 μL) | 200 μL |  |
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This gene encodes an enzyme that belongs to the 3'5'-cyclic nucleotide phosphodiesterase family. Members of this family catalyze hydrolysis of the cyclic nucleotides, cyclic adenosine monophosphate and cyclic guanosine monophosphate, to the corresponding nucleoside 5'-monophosphates. The enzyme encoded by this gene regulates proliferation and migration of vascular smooth muscle cells, and neointimal hyperplasia. This enzyme also plays a role in pathological vascular remodeling by regulating the stability of growth factor receptors, such as PDGF-receptor-beta. [provided by RefSeq, Jul 2016]
Gene Symbol : PDE1C
Gene Name : Phosphodiesterase 1C
Chromosome : CHR 7: 324,282,23-316,167,76
Locus : 7p14.3
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