The protein encoded by this gene is found in the nucleus and is a cofactor of DNA polymerase delta. The encoded protein acts as a homotrimer and helps increase the processivity of leading strand synthesis during DNA replication. In response to DNA damage, this protein is ubiquitinated and is involved in the RAD6-dependent DNA repair pathway. Two transcript variants encoding the same protein have been found for this gene. Pseudogenes of this gene have been described on chromosome 4 and on the X chromosome. [provided by RefSeq, Jul 2008]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| PCNA-20-RE | 20 (40 μL) | 200 μL |  |
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| PCNA-20-OR | 20 (40 μL) | 200 μL |  |
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| PCNA-20-GO | 20 (40 μL) | 200 μL |  |
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| PCNA-20-GR | 20 (40 μL) | 200 μL |  |
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| PCNA-20-AQ | 20 (40 μL) | 200 μL |  |
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The protein encoded by this gene is found in the nucleus and is a cofactor of DNA polymerase delta. The encoded protein acts as a homotrimer and helps increase the processivity of leading strand synthesis during DNA replication. In response to DNA damage, this protein is ubiquitinated and is involved in the RAD6-dependent DNA repair pathway. Two transcript variants encoding the same protein have been found for this gene. Pseudogenes of this gene have been described on chromosome 4 and on the X chromosome. [provided by RefSeq, Jul 2008]
Gene Symbol : PCNA
Gene Name : Proliferating cell nuclear antigen
Chromosome : CHR 20: 512,662,1-511,495,2
Locus : 20p12.3
Alt. Genes : LRPPRC
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