The protein encoded by this gene is a component of centriolar satellites, which are electron dense granules scattered around centrosomes. Inhibition studies show that this protein is essential for the correct localization of several centrosomal proteins, and for anchoring microtubules to the centrosome. Chromosomal aberrations involving this gene are associated with papillary thyroid carcinomas and a variety of hematological malignancies, including atypical chronic myeloid leukemia and T-cell lymphoma. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2015]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| PCM1-20-RE | 20 (40 μL) | 200 μL |  |
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| PCM1-20-OR | 20 (40 μL) | 200 μL |  |
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| PCM1-20-GO | 20 (40 μL) | 200 μL |  |
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| PCM1-20-GR | 20 (40 μL) | 200 μL |  |
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| PCM1-20-AQ | 20 (40 μL) | 200 μL |  |
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The protein encoded by this gene is a component of centriolar satellites, which are electron dense granules scattered around centrosomes. Inhibition studies show that this protein is essential for the correct localization of several centrosomal proteins, and for anchoring microtubules to the centrosome. Chromosomal aberrations involving this gene are associated with papillary thyroid carcinomas and a variety of hematological malignancies, including atypical chronic myeloid leukemia and T-cell lymphoma. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2015]
Gene Symbol : PCM1
Gene Name : Pericentriolar material 1
Chromosome : CHR 8: 179,227,62-180,299,47
Locus : 8p22
Alt. Genes : LRPPRC
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