The protein encoded by this gene contains a RING finger motif, which is most closely related to those of polycomb group (PcG) proteins RNF110/MEL-18 and BMI1. PcG proteins are known to form protein complexes and function as transcription repressors. This protein has been shown to interact with some PcG proteins and act as a transcription repressor. The activity of this protein is found to be regulated by cell cycle dependent phosphorylation. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| PCGF6-20-RE | 20 (40 μL) | 200 μL |  |
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| PCGF6-20-OR | 20 (40 μL) | 200 μL |  |
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| PCGF6-20-GO | 20 (40 μL) | 200 μL |  |
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| PCGF6-20-GR | 20 (40 μL) | 200 μL |  |
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| PCGF6-20-AQ | 20 (40 μL) | 200 μL |  |
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The protein encoded by this gene contains a RING finger motif, which is most closely related to those of polycomb group (PcG) proteins RNF110/MEL-18 and BMI1. PcG proteins are known to form protein complexes and function as transcription repressors. This protein has been shown to interact with some PcG proteins and act as a transcription repressor. The activity of this protein is found to be regulated by cell cycle dependent phosphorylation. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008]
Gene Symbol : PCGF6
Gene Name : Polycomb group ring finger 6
Chromosome : CHR 10: 103,351,133-103,302,795
Locus : 10q24.33
Alt. Genes : ENAM
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