This gene is a member of the paired box (PAX) family of transcription factors. Members of the PAX family typically contain a paired box domain and a paired-type homeodomain. These genes play critical roles during fetal development. This gene plays a role in pattern formation during embryogenesis and may be essential for development of the vertebral column. This gene is silenced by methylation in ovarian and cervical cancers and may be a tumor suppressor gene. Mutations in this gene are also associated with vertebral malformations. [provided by RefSeq, Mar 2012]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| PAX1-20-RE | 20 (40 μL) | 200 μL |  |
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| PAX1-20-OR | 20 (40 μL) | 200 μL |  |
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| PAX1-20-GO | 20 (40 μL) | 200 μL |  |
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| PAX1-20-GR | 20 (40 μL) | 200 μL |  |
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| PAX1-20-AQ | 20 (40 μL) | 200 μL |  |
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This gene is a member of the paired box (PAX) family of transcription factors. Members of the PAX family typically contain a paired box domain and a paired-type homeodomain. These genes play critical roles during fetal development. This gene plays a role in pattern formation during embryogenesis and may be essential for development of the vertebral column. This gene is silenced by methylation in ovarian and cervical cancers and may be a tumor suppressor gene. Mutations in this gene are also associated with vertebral malformations. [provided by RefSeq, Mar 2012]
Gene Symbol : PAX1
Gene Name : Paired box 1
Chromosome : CHR 20: 217,056,58-217,184,85
Locus : 20p11.22
Alt. Genes : SGK2
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