The product of this gene belongs to the family of P2 receptors, which is activated by extracellular nucleotides and subdivided into P2X ligand-gated ion channels and P2Y G-protein coupled receptors. This family has several receptor subtypes with different pharmacological selectivity, which overlaps in some cases, for various adenosine and uridine nucleotides. This receptor, which is a G-protein coupled receptor, is responsive to UDP, partially responsive to UTP and ADP, and not responsive to ATP. It is proposed that this receptor mediates inflammatory responses. Alternative splicing results in multiple transcript variants that encode different protein isoforms. [provided by RefSeq, Mar 2013]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| P2RY6-20-RE | 20 (40 μL) | 200 μL |  |
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| P2RY6-20-OR | 20 (40 μL) | 200 μL |  |
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| P2RY6-20-GO | 20 (40 μL) | 200 μL |  |
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| P2RY6-20-GR | 20 (40 μL) | 200 μL |  |
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| P2RY6-20-AQ | 20 (40 μL) | 200 μL |  |
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The product of this gene belongs to the family of P2 receptors, which is activated by extracellular nucleotides and subdivided into P2X ligand-gated ion channels and P2Y G-protein coupled receptors. This family has several receptor subtypes with different pharmacological selectivity, which overlaps in some cases, for various adenosine and uridine nucleotides. This receptor, which is a G-protein coupled receptor, is responsive to UDP, partially responsive to UTP and ADP, and not responsive to ATP. It is proposed that this receptor mediates inflammatory responses. Alternative splicing results in multiple transcript variants that encode different protein isoforms. [provided by RefSeq, Mar 2013]
Gene Symbol : P2RY6
Gene Name : Pyrimidinergic receptor P2Y6
Chromosome : CHR 11: 732,645,02-732,986,24
Locus : 11q13.4
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