P2RX7 FISH Probe

The product of this gene belongs to the family of purinoceptors for ATP. This receptor functions as a ligand-gated ion channel and is responsible for ATP-dependent lysis of macrophages through the formation of membrane pores permeable to large molecules. Activation of this nuclear receptor by ATP in the cytoplasm may be a mechanism by which cellular activity can be coupled to changes in gene expression. Multiple alternatively spliced variants have been identified, most of which fit nonsense-mediated decay (NMD) criteria. [provided by RefSeq, Jul 2010]


Gene Details
SKU Test Kits Buffer Dye Color Order Now
P2RX7-20-RE 20 (40 μL) 200 μL color Request Pricing
P2RX7-20-OR 20 (40 μL) 200 μL color Request Pricing
P2RX7-20-GO 20 (40 μL) 200 μL color Request Pricing
P2RX7-20-GR 20 (40 μL) 200 μL color Request Pricing
P2RX7-20-AQ 20 (40 μL) 200 μL color Request Pricing

Gene Summary

The product of this gene belongs to the family of purinoceptors for ATP. This receptor functions as a ligand-gated ion channel and is responsible for ATP-dependent lysis of macrophages through the formation of membrane pores permeable to large molecules. Activation of this nuclear receptor by ATP in the cytoplasm may be a mechanism by which cellular activity can be coupled to changes in gene expression. Multiple alternatively spliced variants have been identified, most of which fit nonsense-mediated decay (NMD) criteria. [provided by RefSeq, Jul 2010]

Gene Details

Gene Symbol : P2RX7

Gene Name : Purinergic receptor P2X 7

Chromosome : CHR 12: 121,132,818-121,189,477

Locus : 12q24.31

Alt. Genes : CEBPZ

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