This gene encodes a member of the family of neuronal petraxins, synaptic proteins that are related to C-reactive protein. This protein is involved in excitatory synapse formation. It also plays a role in clustering of alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA)-type glutamate receptors at established synapses, resulting in non-apoptotic cell death of dopaminergic nerve cells. Up-regulation of this gene in Parkinson disease (PD) tissues suggests that the protein may be involved in the pathology of PD. [provided by RefSeq, Feb 2009]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| NPTX2-20-RE | 20 (40 μL) | 200 μL |  |
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| NPTX2-20-OR | 20 (40 μL) | 200 μL |  |
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| NPTX2-20-GO | 20 (40 μL) | 200 μL |  |
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| NPTX2-20-GR | 20 (40 μL) | 200 μL |  |
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| NPTX2-20-AQ | 20 (40 μL) | 200 μL |  |
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This gene encodes a member of the family of neuronal petraxins, synaptic proteins that are related to C-reactive protein. This protein is involved in excitatory synapse formation. It also plays a role in clustering of alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA)-type glutamate receptors at established synapses, resulting in non-apoptotic cell death of dopaminergic nerve cells. Up-regulation of this gene in Parkinson disease (PD) tissues suggests that the protein may be involved in the pathology of PD. [provided by RefSeq, Feb 2009]
Gene Symbol : NPTX2
Gene Name : Neuronal pentraxin 2
Chromosome : CHR 7: 986,172,84-986,298,68
Locus : 7q22.1
Alt. Genes : PREB
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