This gene is a member of the natriuretic peptide family and encodes a secreted protein which functions as a cardiac hormone. The protein undergoes two cleavage events, one within the cell and a second after secretion into the blood. The protein's biological actions include natriuresis, diuresis, vasorelaxation, inhibition of renin and aldosterone secretion, and a key role in cardiovascular homeostasis. A high concentration of this protein in the bloodstream is indicative of heart failure. The protein also acts as an antimicrobial peptide with antibacterial and antifungal activity. Mutations in this gene have been associated with postmenopausal osteoporosis. [provided by RefSeq, Nov 2014]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| NPPB-20-RE | 20 (40 μL) | 200 μL |  |
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| NPPB-20-OR | 20 (40 μL) | 200 μL |  |
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| NPPB-20-GO | 20 (40 μL) | 200 μL |  |
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| NPPB-20-GR | 20 (40 μL) | 200 μL |  |
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| NPPB-20-AQ | 20 (40 μL) | 200 μL |  |
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This gene is a member of the natriuretic peptide family and encodes a secreted protein which functions as a cardiac hormone. The protein undergoes two cleavage events, one within the cell and a second after secretion into the blood. The protein's biological actions include natriuresis, diuresis, vasorelaxation, inhibition of renin and aldosterone secretion, and a key role in cardiovascular homeostasis. A high concentration of this protein in the bloodstream is indicative of heart failure. The protein also acts as an antimicrobial peptide with antibacterial and antifungal activity. Mutations in this gene have been associated with postmenopausal osteoporosis. [provided by RefSeq, Nov 2014]
Gene Symbol : NPPB
Gene Name : Natriuretic peptide B
Chromosome : CHR 1: 118,589,34-118,574,63
Locus : 1p36.22
Alt. Genes : RCL1
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