This gene encodes a protein that is involved in the activation of the ubiquitous transcription factor NF-kappaB. This protein is associated with the the histone deacetylase HDAC3 and with the Notch corepressor complex, and it thereby acts as a transcriptional repressor of Notch target genes. It is also required for alphabeta T cell development. A related pseudogene has been identified on chromosome X, while a related and intronless retrocopy, which has an intact CDS and may be functional, is located on chromosome 6. [provided by RefSeq, May 2010]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| NKAP-20-RE | 20 (40 μL) | 200 μL |  |
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| NKAP-20-OR | 20 (40 μL) | 200 μL |  |
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| NKAP-20-GO | 20 (40 μL) | 200 μL |  |
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| NKAP-20-GR | 20 (40 μL) | 200 μL |  |
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| NKAP-20-AQ | 20 (40 μL) | 200 μL |  |
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This gene encodes a protein that is involved in the activation of the ubiquitous transcription factor NF-kappaB. This protein is associated with the the histone deacetylase HDAC3 and with the Notch corepressor complex, and it thereby acts as a transcriptional repressor of Notch target genes. It is also required for alphabeta T cell development. A related pseudogene has been identified on chromosome X, while a related and intronless retrocopy, which has an intact CDS and may be functional, is located on chromosome 6. [provided by RefSeq, May 2010]
Gene Symbol : NKAP
Gene Name : NFKB activating protein
Chromosome : CHR X: 119,943,771-119,925,049
Locus : Xq24
Alt. Genes : CELA3A
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