This gene encodes a nuclear receptor co-repressor that mediates transcriptional silencing of certain target genes. The encoded protein is a member of a family of thyroid hormone- and retinoic acid receptor-associated co-repressors. This protein acts as part of a multisubunit complex which includes histone deacetylases to modify chromatin structure that prevents basal transcriptional activity of target genes. Aberrant expression of this gene is associated with certain cancers. Alternate splicing results in multiple transcript variants encoding different isoforms.[provided by RefSeq, Apr 2011]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| NCOR2-20-RE | 20 (40 μL) | 200 μL |  |
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| NCOR2-20-OR | 20 (40 μL) | 200 μL |  |
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| NCOR2-20-GO | 20 (40 μL) | 200 μL |  |
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| NCOR2-20-GR | 20 (40 μL) | 200 μL |  |
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| NCOR2-20-AQ | 20 (40 μL) | 200 μL |  |
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This gene encodes a nuclear receptor co-repressor that mediates transcriptional silencing of certain target genes. The encoded protein is a member of a family of thyroid hormone- and retinoic acid receptor-associated co-repressors. This protein acts as part of a multisubunit complex which includes histone deacetylases to modify chromatin structure that prevents basal transcriptional activity of target genes. Aberrant expression of this gene is associated with certain cancers. Alternate splicing results in multiple transcript variants encoding different isoforms.[provided by RefSeq, Apr 2011]
Gene Symbol : NCOR2
Gene Name : Nuclear receptor corepressor 2
Chromosome : CHR 12: 124,567,463-124,324,410
Locus : 12q24.31
Alt. Genes : SUGP2
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