This gene encodes a member of the family of NGFI-A binding (NAB) proteins, which function in the nucleus to repress transcription induced by some members of the EGR (early growth response) family of transactivators. NAB proteins can homo- or hetero-multimerize with other EGR or NAB proteins through a conserved N-terminal domain, and repress transcription through two partially redundant C-terminal domains. Transcriptional repression by the encoded protein is mediated in part by interactions with the nucleosome remodeling and deactylase (NuRD) complex. Alternatively spliced transcript variants have been described, but their biological validity has not been determined. [provided by RefSeq, Jul 2008]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| NAB2-20-RE | 20 (40 μL) | 200 μL |  |
Request Pricing |
| NAB2-20-OR | 20 (40 μL) | 200 μL |  |
Request Pricing |
| NAB2-20-GO | 20 (40 μL) | 200 μL |  |
Request Pricing |
| NAB2-20-GR | 20 (40 μL) | 200 μL |  |
Request Pricing |
| NAB2-20-AQ | 20 (40 μL) | 200 μL |  |
Request Pricing |
This gene encodes a member of the family of NGFI-A binding (NAB) proteins, which function in the nucleus to repress transcription induced by some members of the EGR (early growth response) family of transactivators. NAB proteins can homo- or hetero-multimerize with other EGR or NAB proteins through a conserved N-terminal domain, and repress transcription through two partially redundant C-terminal domains. Transcriptional repression by the encoded protein is mediated in part by interactions with the nucleosome remodeling and deactylase (NuRD) complex. Alternatively spliced transcript variants have been described, but their biological validity has not been determined. [provided by RefSeq, Jul 2008]
Gene Symbol : NAB2
Gene Name : NGFI-A binding protein 2
Chromosome : CHR 12: 570,888,93-570,954,75
Locus : 12q13.3
Alt. Genes : OPTN
Lorem Ipsum is simply dummy text of the printing and typesetting industry.
Lorem Ipsum is simply dummy text of the printing and typesetting industry.