This gene encodes a nuclear protein that is similar to the product of the Drosophila male-specific lethal-3 gene. The Drosophila protein plays a critical role in a dosage-compensation pathway, which equalizes X-linked gene expression in males and females. Thus, the human protein is thought to play a similar function in chromatin remodeling and transcriptional regulation, and it has been found as part of a complex that is responsible for histone H4 lysine-16 acetylation. This gene can undergo X inactivation. Alternative splicing results in multiple transcript variants. Related pseudogenes have been identified on chromosomes 2, 7 and 8. [provided by RefSeq, Jul 2010]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| MSL3-20-RE | 20 (40 μL) | 200 μL |  |
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| MSL3-20-OR | 20 (40 μL) | 200 μL |  |
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| MSL3-20-GO | 20 (40 μL) | 200 μL |  |
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| MSL3-20-GR | 20 (40 μL) | 200 μL |  |
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| MSL3-20-AQ | 20 (40 μL) | 200 μL |  |
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This gene encodes a nuclear protein that is similar to the product of the Drosophila male-specific lethal-3 gene. The Drosophila protein plays a critical role in a dosage-compensation pathway, which equalizes X-linked gene expression in males and females. Thus, the human protein is thought to play a similar function in chromatin remodeling and transcriptional regulation, and it has been found as part of a complex that is responsible for histone H4 lysine-16 acetylation. This gene can undergo X inactivation. Alternative splicing results in multiple transcript variants. Related pseudogenes have been identified on chromosomes 2, 7 and 8. [provided by RefSeq, Jul 2010]
Gene Symbol : MSL3
Gene Name : MSL complex subunit 3
Chromosome : CHR X: 117,581,58-117,757,52
Locus : Xp22.2
Alt. Genes : HIPK3
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