The protein encoded by this gene forms a heterodimer with MSH2 to form MutS beta, part of the post-replicative DNA mismatch repair system. MutS beta initiates mismatch repair by binding to a mismatch and then forming a complex with MutL alpha heterodimer. This gene contains a polymorphic 9 bp tandem repeat sequence in the first exon. The repeat is present 6 times in the reference genome sequence and 3-7 repeats have been reported. Defects in this gene are a cause of susceptibility to endometrial cancer. [provided by RefSeq, Mar 2011]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| MSH3-20-RE | 20 (40 μL) | 200 μL |  |
Request Pricing |
| MSH3-20-OR | 20 (40 μL) | 200 μL |  |
Request Pricing |
| MSH3-20-GO | 20 (40 μL) | 200 μL |  |
Request Pricing |
| MSH3-20-GR | 20 (40 μL) | 200 μL |  |
Request Pricing |
| MSH3-20-AQ | 20 (40 μL) | 200 μL |  |
Request Pricing |
The protein encoded by this gene forms a heterodimer with MSH2 to form MutS beta, part of the post-replicative DNA mismatch repair system. MutS beta initiates mismatch repair by binding to a mismatch and then forming a complex with MutL alpha heterodimer. This gene contains a polymorphic 9 bp tandem repeat sequence in the first exon. The repeat is present 6 times in the reference genome sequence and 3-7 repeats have been reported. Defects in this gene are a cause of susceptibility to endometrial cancer. [provided by RefSeq, Mar 2011]
Gene Symbol : MSH3
Gene Name : MutS homolog 3
Chromosome : CHR 5: 806,546,47-808,768,14
Locus : 5q14.1
Lorem Ipsum is simply dummy text of the printing and typesetting industry.
Lorem Ipsum is simply dummy text of the printing and typesetting industry.