MRPL20 FISH Probe

Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein. A pseudogene corresponding to this gene is found on chromosome 21q. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jan 2016]


Gene Details
SKU Test Kits Buffer Dye Color Order Now
MRPL20-20-RE 20 (40 μL) 200 μL color Request Pricing
MRPL20-20-OR 20 (40 μL) 200 μL color Request Pricing
MRPL20-20-GO 20 (40 μL) 200 μL color Request Pricing
MRPL20-20-GR 20 (40 μL) 200 μL color Request Pricing
MRPL20-20-AQ 20 (40 μL) 200 μL color Request Pricing

Gene Summary

Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein. A pseudogene corresponding to this gene is found on chromosome 21q. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jan 2016]

Gene Details

Gene Symbol : MRPL20

Gene Name : Mitochondrial ribosomal protein L20

Chromosome : CHR 1: 140,731,2-140,189,5

Locus : 1p36.33

Alt. Genes : HIPK3

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