The protein encoded by this gene forms a complex with tonsoku-like, DNA repair protein (TONSL), and this complex recognizes and repairs DNA double-strand breaks at sites of stalled or collapsed replication forks. The encoded protein also can bind with the histone-associated protein NFKBIL2 to help regulate the chromatin state at stalled replication forks. Finally, this gene appears to be overexpressed in most lung and esophageal cancers. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Apr 2017]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| MMS22L-20-RE | 20 (40 μL) | 200 μL |  |
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| MMS22L-20-OR | 20 (40 μL) | 200 μL |  |
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| MMS22L-20-GO | 20 (40 μL) | 200 μL |  |
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| MMS22L-20-GR | 20 (40 μL) | 200 μL |  |
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| MMS22L-20-AQ | 20 (40 μL) | 200 μL |  |
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The protein encoded by this gene forms a complex with tonsoku-like, DNA repair protein (TONSL), and this complex recognizes and repairs DNA double-strand breaks at sites of stalled or collapsed replication forks. The encoded protein also can bind with the histone-associated protein NFKBIL2 to help regulate the chromatin state at stalled replication forks. Finally, this gene appears to be overexpressed in most lung and esophageal cancers. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Apr 2017]
Gene Symbol : MMS22L
Gene Name : MMS22 like, DNA repair protein
Chromosome : CHR 6: 972,834,36-971,421,60
Locus : 6q16.1
Alt. Genes : FEM1B
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