MMP13 FISH Probe

This gene encodes a member of the peptidase M10 family of matrix metalloproteinases (MMPs). Proteins in this family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. The encoded preproprotein is proteolytically processed to generate the mature protease. This protease cleaves type II collagen more efficiently than types I and III. It may be involved in articular cartilage turnover and cartilage pathophysiology associated with osteoarthritis. Mutations in this gene are associated with metaphyseal anadysplasia. This gene is part of a cluster of MMP genes on chromosome 11. [provided by RefSeq, Jan 2016]


Gene Details
SKU Test Kits Buffer Dye Color Order Now
MMP13-20-RE 20 (40 μL) 200 μL color Request Pricing
MMP13-20-OR 20 (40 μL) 200 μL color Request Pricing
MMP13-20-GO 20 (40 μL) 200 μL color Request Pricing
MMP13-20-GR 20 (40 μL) 200 μL color Request Pricing
MMP13-20-AQ 20 (40 μL) 200 μL color Request Pricing

Gene Summary

This gene encodes a member of the peptidase M10 family of matrix metalloproteinases (MMPs). Proteins in this family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. The encoded preproprotein is proteolytically processed to generate the mature protease. This protease cleaves type II collagen more efficiently than types I and III. It may be involved in articular cartilage turnover and cartilage pathophysiology associated with osteoarthritis. Mutations in this gene are associated with metaphyseal anadysplasia. This gene is part of a cluster of MMP genes on chromosome 11. [provided by RefSeq, Jan 2016]

Gene Details

Gene Symbol : MMP13

Gene Name : Matrix metallopeptidase 13

Chromosome : CHR 11: 102,955,733-102,942,991

Locus : 11q22.2

Alt. Genes : EBI3

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