This gene encodes an essential regulator of mitochondrial Ca2+ uptake under basal conditions. The encoded protein interacts with the mitochondrial calcium uniporter, a mitochondrial inner membrane Ca2+ channel, and is essential in preventing mitochondrial Ca2+ overload, which can cause excessive production of reactive oxygen species and cell stress. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Mar 2013]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| MICU1-20-RE | 20 (40 μL) | 200 μL |  |
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| MICU1-20-OR | 20 (40 μL) | 200 μL |  |
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| MICU1-20-GO | 20 (40 μL) | 200 μL |  |
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| MICU1-20-GR | 20 (40 μL) | 200 μL |  |
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| MICU1-20-AQ | 20 (40 μL) | 200 μL |  |
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This gene encodes an essential regulator of mitochondrial Ca2+ uptake under basal conditions. The encoded protein interacts with the mitochondrial calcium uniporter, a mitochondrial inner membrane Ca2+ channel, and is essential in preventing mitochondrial Ca2+ overload, which can cause excessive production of reactive oxygen species and cell stress. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Mar 2013]
Gene Symbol : MICU1
Gene Name : Mitochondrial calcium uptake 1
Chromosome : CHR 10: 726,261,90-723,673,25
Locus : 10q22.1
Alt. Genes : RAD50
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