This gene encodes a protein containing multiple ankyrin repeats and RING finger domains that functions as an E3 ubiquitin ligase. The encoded protein positively regulates Notch signaling by ubiquitinating the Notch receptors, thereby facilitating their endocytosis. This protein may also promote the ubiquitination and degradation of death-associated protein kinase 1 (DAPK1). [provided by RefSeq, Jun 2013]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| MIB1-20-RE | 20 (40 μL) | 200 μL |  |
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| MIB1-20-OR | 20 (40 μL) | 200 μL |  |
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| MIB1-20-GO | 20 (40 μL) | 200 μL |  |
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| MIB1-20-GR | 20 (40 μL) | 200 μL |  |
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| MIB1-20-AQ | 20 (40 μL) | 200 μL |  |
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This gene encodes a protein containing multiple ankyrin repeats and RING finger domains that functions as an E3 ubiquitin ligase. The encoded protein positively regulates Notch signaling by ubiquitinating the Notch receptors, thereby facilitating their endocytosis. This protein may also promote the ubiquitination and degradation of death-associated protein kinase 1 (DAPK1). [provided by RefSeq, Jun 2013]
Gene Symbol : MIB1
Gene Name : Mindbomb E3 ubiquitin protein ligase 1
Chromosome : CHR 18: 217,407,92-218,709,56
Locus : 18q11.2
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