This gene encodes a member of the multiple epidermal growth factor-like domains protein family. The encoded protein plays a role in cell adhesion, motility and proliferation, and is a critical mediator of apoptotic cell phagocytosis as well as amyloid-beta peptide uptake in the brain. Expression of this gene may be associated with schizophrenia, and mutations in this gene are a cause of early-onset myopathy, areflexia, respiratory distress, and dysphagia (EMARDD) as well as congenital myopathy with minicores. Alternatively spliced transcript variants have been observed for this gene. [provided by RefSeq, Apr 2012]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| MEGF10-20-RE | 20 (40 μL) | 200 μL |  |
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| MEGF10-20-OR | 20 (40 μL) | 200 μL |  |
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| MEGF10-20-GO | 20 (40 μL) | 200 μL |  |
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| MEGF10-20-GR | 20 (40 μL) | 200 μL |  |
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| MEGF10-20-AQ | 20 (40 μL) | 200 μL |  |
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This gene encodes a member of the multiple epidermal growth factor-like domains protein family. The encoded protein plays a role in cell adhesion, motility and proliferation, and is a critical mediator of apoptotic cell phagocytosis as well as amyloid-beta peptide uptake in the brain. Expression of this gene may be associated with schizophrenia, and mutations in this gene are a cause of early-onset myopathy, areflexia, respiratory distress, and dysphagia (EMARDD) as well as congenital myopathy with minicores. Alternatively spliced transcript variants have been observed for this gene. [provided by RefSeq, Apr 2012]
Gene Symbol : MEGF10
Gene Name : Multiple EGF like domains 10
Chromosome : CHR 5: 127,229,518-127,461,221
Locus : 5q23.2
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