MARCH11 is a member of the MARCH family of membrane-bound E3 ubiquitin ligases (EC 6.3.2.19). These enzymes add ubiquitin (see MIM 191339) to target lysines in substrate proteins, thereby signaling their intracellular transport. March11 appears to have a role in ubiquitin-mediated protein sorting in the trans-Golgi network (TGN)-multivesicular body (MVB) transport pathway (Morokuma et al., 2007 [PubMed 17604280]).[supplied by OMIM, Apr 2010]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| MARCH11-20-RE | 20 (40 μL) | 200 μL |  |
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| MARCH11-20-OR | 20 (40 μL) | 200 μL |  |
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| MARCH11-20-GO | 20 (40 μL) | 200 μL |  |
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| MARCH11-20-GR | 20 (40 μL) | 200 μL |  |
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| MARCH11-20-AQ | 20 (40 μL) | 200 μL |  |
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MARCH11 is a member of the MARCH family of membrane-bound E3 ubiquitin ligases (EC 6.3.2.19). These enzymes add ubiquitin (see MIM 191339) to target lysines in substrate proteins, thereby signaling their intracellular transport. March11 appears to have a role in ubiquitin-mediated protein sorting in the trans-Golgi network (TGN)-multivesicular body (MVB) transport pathway (Morokuma et al., 2007 [PubMed 17604280]).[supplied by OMIM, Apr 2010]
Gene Symbol : MARCH11
Gene Name : Membrane associated ring-CH-type finger 11
Chromosome : CHR 5: 161,797,87-160,673,64
Locus : 5p15.1
Alt. Genes : HIPK3
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