The protein encoded by this gene is a DNA-binding, leucine zipper-containing transcription factor that acts as a homodimer or as a heterodimer. Depending on the binding site and binding partner, the encoded protein can be a transcriptional activator or repressor. This protein plays a role in the regulation of several cellular processes, including embryonic lens fiber cell development, increased T-cell susceptibility to apoptosis, and chondrocyte terminal differentiation. Defects in this gene are a cause of juvenile-onset pulverulent cataract as well as congenital cerulean cataract 4 (CCA4). Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2010]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| MAF-20-RE | 20 (40 μL) | 200 μL |  |
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| MAF-20-OR | 20 (40 μL) | 200 μL |  |
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| MAF-20-GO | 20 (40 μL) | 200 μL |  |
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| MAF-20-GR | 20 (40 μL) | 200 μL |  |
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| MAF-20-AQ | 20 (40 μL) | 200 μL |  |
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The protein encoded by this gene is a DNA-binding, leucine zipper-containing transcription factor that acts as a homodimer or as a heterodimer. Depending on the binding site and binding partner, the encoded protein can be a transcriptional activator or repressor. This protein plays a role in the regulation of several cellular processes, including embryonic lens fiber cell development, increased T-cell susceptibility to apoptosis, and chondrocyte terminal differentiation. Defects in this gene are a cause of juvenile-onset pulverulent cataract as well as congenital cerulean cataract 4 (CCA4). Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2010]
Gene Symbol : MAF
Gene Name : MAF bZIP transcription factor
Chromosome : CHR 16: 796,007,24-792,026,23
Locus : 16q23.2
Alt. Genes : RBM5
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