This gene is a member of the leucine-rich repeat kinase family and encodes a protein with an ankryin repeat region, a leucine-rich repeat (LRR) domain, a kinase domain, a DFG-like motif, a RAS domain, a GTPase domain, a MLK-like domain, and a WD40 domain. The protein is present largely in the cytoplasm but also associates with the mitochondrial outer membrane. Mutations in this gene have been associated with Parkinson disease-8. [provided by RefSeq, Jul 2008]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| LRRK2-20-RE | 20 (40 μL) | 200 μL |  |
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| LRRK2-20-OR | 20 (40 μL) | 200 μL |  |
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| LRRK2-20-GO | 20 (40 μL) | 200 μL |  |
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| LRRK2-20-GR | 20 (40 μL) | 200 μL |  |
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| LRRK2-20-AQ | 20 (40 μL) | 200 μL |  |
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This gene is a member of the leucine-rich repeat kinase family and encodes a protein with an ankryin repeat region, a leucine-rich repeat (LRR) domain, a kinase domain, a DFG-like motif, a RAS domain, a GTPase domain, a MLK-like domain, and a WD40 domain. The protein is present largely in the cytoplasm but also associates with the mitochondrial outer membrane. Mutations in this gene have been associated with Parkinson disease-8. [provided by RefSeq, Jul 2008]
Gene Symbol : LRRK2
Gene Name : Leucine rich repeat kinase 2
Chromosome : CHR 12: 402,248,94-403,692,84
Locus : 12q12
Alt. Genes : ZNF263
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