This gene encodes a member of the low density lipoprotein receptor (LDLR) family. Low density lipoprotein receptors are cell surface proteins that play roles in both signal transduction and receptor-mediated endocytosis of specific ligands for lysosomal degradation. The encoded protein plays a critical role in the migration of neurons during development by mediating Reelin signaling, and also functions as a receptor for the cholesterol transport protein apolipoprotein E. Expression of this gene may be a marker for major depressive disorder. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Jun 2011]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| LRP8-20-RE | 20 (40 μL) | 200 μL |  |
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| LRP8-20-OR | 20 (40 μL) | 200 μL |  |
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| LRP8-20-GO | 20 (40 μL) | 200 μL |  |
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| LRP8-20-GR | 20 (40 μL) | 200 μL |  |
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| LRP8-20-AQ | 20 (40 μL) | 200 μL |  |
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This gene encodes a member of the low density lipoprotein receptor (LDLR) family. Low density lipoprotein receptors are cell surface proteins that play roles in both signal transduction and receptor-mediated endocytosis of specific ligands for lysosomal degradation. The encoded protein plays a critical role in the migration of neurons during development by mediating Reelin signaling, and also functions as a receptor for the cholesterol transport protein apolipoprotein E. Expression of this gene may be a marker for major depressive disorder. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Jun 2011]
Gene Symbol : LRP8
Gene Name : LDL receptor related protein 8
Chromosome : CHR 1: 533,281,48-532,423,63
Locus : 1p32.3
Alt. Genes : CELA3A
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