The lethal (2) giant larvae protein of Drosophila plays a role in asymmetric cell division, epithelial cell polarity, and cell migration. This human gene encodes a protein similar to lethal (2) giant larvae of Drosophila. In fly, the protein's ability to localize cell fate determinants is regulated by the atypical protein kinase C (aPKC). In human, this protein interacts with aPKC-containing complexes and is cortically localized in mitotic cells. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| LLGL2-20-RE | 20 (40 μL) | 200 μL |  |
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| LLGL2-20-OR | 20 (40 μL) | 200 μL |  |
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| LLGL2-20-GO | 20 (40 μL) | 200 μL |  |
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| LLGL2-20-GR | 20 (40 μL) | 200 μL |  |
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| LLGL2-20-AQ | 20 (40 μL) | 200 μL |  |
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The lethal (2) giant larvae protein of Drosophila plays a role in asymmetric cell division, epithelial cell polarity, and cell migration. This human gene encodes a protein similar to lethal (2) giant larvae of Drosophila. In fly, the protein's ability to localize cell fate determinants is regulated by the atypical protein kinase C (aPKC). In human, this protein interacts with aPKC-containing complexes and is cortically localized in mitotic cells. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]
Gene Symbol : LLGL2
Gene Name : LLGL2, scribble cell polarity complex component
Chromosome : CHR 17: 755,250,79-755,752,08
Locus : 17q25.1
Alt. Genes : AKAP9
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