This gene produces a long non-coding RNA that regulates the reprogramming of pluripotent stem cells. This RNA suppresses induction of tumor protein p53 after DNA damage. It is thought to act as a sponge for microRNAs that regulate stem cell factors POU class 5 homeobox 1, Nanog, and SRY-box 2. This RNA may also have a extracellular role in modulating response to hypoxia in hepatocellular cancer cells. Expression of this transcript is associated with tumor progression and epithelial to mesenchymal transition and metastasis. [provided by RefSeq, Dec 2017]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| LINC-ROR-20-RE | 20 (40 μL) | 200 μL |  |
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| LINC-ROR-20-OR | 20 (40 μL) | 200 μL |  |
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| LINC-ROR-20-GO | 20 (40 μL) | 200 μL |  |
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| LINC-ROR-20-GR | 20 (40 μL) | 200 μL |  |
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| LINC-ROR-20-AQ | 20 (40 μL) | 200 μL |  |
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This gene produces a long non-coding RNA that regulates the reprogramming of pluripotent stem cells. This RNA suppresses induction of tumor protein p53 after DNA damage. It is thought to act as a sponge for microRNAs that regulate stem cell factors POU class 5 homeobox 1, Nanog, and SRY-box 2. This RNA may also have a extracellular role in modulating response to hypoxia in hepatocellular cancer cells. Expression of this transcript is associated with tumor progression and epithelial to mesenchymal transition and metastasis. [provided by RefSeq, Dec 2017]
Gene Symbol : LINC-ROR
Gene Name : Long intergenic non-protein coding RNA, regulator of reprogramming
Chromosome : CHR 18: 570,721,18-570,545,70
Locus : 18q21.31
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