This gene encodes the B subunit of lactate dehydrogenase enzyme, which catalyzes the interconversion of pyruvate and lactate with concomitant interconversion of NADH and NAD+ in a post-glycolysis process. Alternatively spliced transcript variants have been found for this gene. Recent studies have shown that a C-terminally extended isoform is produced by use of an alternative in-frame translation termination codon via a stop codon readthrough mechanism, and that this isoform is localized in the peroxisomes. Mutations in this gene are associated with lactate dehydrogenase B deficiency. Pseudogenes have been identified on chromosomes X, 5 and 13. [provided by RefSeq, Feb 2016]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| LDHB-20-RE | 20 (40 μL) | 200 μL |  |
Request Pricing |
| LDHB-20-OR | 20 (40 μL) | 200 μL |  |
Request Pricing |
| LDHB-20-GO | 20 (40 μL) | 200 μL |  |
Request Pricing |
| LDHB-20-GR | 20 (40 μL) | 200 μL |  |
Request Pricing |
| LDHB-20-AQ | 20 (40 μL) | 200 μL |  |
Request Pricing |
This gene encodes the B subunit of lactate dehydrogenase enzyme, which catalyzes the interconversion of pyruvate and lactate with concomitant interconversion of NADH and NAD+ in a post-glycolysis process. Alternatively spliced transcript variants have been found for this gene. Recent studies have shown that a C-terminally extended isoform is produced by use of an alternative in-frame translation termination codon via a stop codon readthrough mechanism, and that this isoform is localized in the peroxisomes. Mutations in this gene are associated with lactate dehydrogenase B deficiency. Pseudogenes have been identified on chromosomes X, 5 and 13. [provided by RefSeq, Feb 2016]
Gene Symbol : LDHB
Gene Name : Lactate dehydrogenase B
Chromosome : CHR 12: 216,579,70-216,353,41
Locus : 12p12.1
Alt. Genes : CEBPZ
Lorem Ipsum is simply dummy text of the printing and typesetting industry.
Lorem Ipsum is simply dummy text of the printing and typesetting industry.