This gene encodes a scaffold protein that functions in the extracellular signal-regulated kinase (ERK) cascade. The protein is localized to late endosomes by the mitogen-activated protein-binding protein-interacting protein, and binds specifically to MAP kinase kinase MAP2K1/MEK1, MAP kinase MAPK3/ERK1, and MAP kinase MAPK1/ERK2. Studies of the orthologous gene in mouse indicate that it regulates late endosomal traffic and cell proliferation. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. A pseudogene of this gene is located on the long arm of chromosome 13. [provided by RefSeq, Aug 2011]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| LAMTOR3-20-RE | 20 (40 μL) | 200 μL |  |
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| LAMTOR3-20-OR | 20 (40 μL) | 200 μL |  |
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| LAMTOR3-20-GO | 20 (40 μL) | 200 μL |  |
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| LAMTOR3-20-GR | 20 (40 μL) | 200 μL |  |
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| LAMTOR3-20-AQ | 20 (40 μL) | 200 μL |  |
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This gene encodes a scaffold protein that functions in the extracellular signal-regulated kinase (ERK) cascade. The protein is localized to late endosomes by the mitogen-activated protein-binding protein-interacting protein, and binds specifically to MAP kinase kinase MAP2K1/MEK1, MAP kinase MAPK3/ERK1, and MAP kinase MAPK1/ERK2. Studies of the orthologous gene in mouse indicate that it regulates late endosomal traffic and cell proliferation. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. A pseudogene of this gene is located on the long arm of chromosome 13. [provided by RefSeq, Aug 2011]
Gene Symbol : LAMTOR3
Gene Name : Late endosomal/lysosomal adaptor, MAPK and MTOR activator 3
Chromosome : CHR 4: 998,945,45-998,783,37
Locus : 4q23
Alt. Genes : RAD50
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