This gene encodes a member of the malignant brain tumor (MBT) family of chromatin interacting transcriptional repressors. Members of this family function as methyl-lysine readers, which recognize methylated lysine residues on histone protein tails, and are associated with the repression of gene expression. The encoded protein may regulate hematopoiesis. Homozygous deletion of this gene has been observed in human patients with medulloblastoma. [provided by RefSeq, Oct 2016]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| L3MBTL3-20-RE | 20 (40 μL) | 200 μL |  |
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| L3MBTL3-20-OR | 20 (40 μL) | 200 μL |  |
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| L3MBTL3-20-GO | 20 (40 μL) | 200 μL |  |
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| L3MBTL3-20-GR | 20 (40 μL) | 200 μL |  |
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| L3MBTL3-20-AQ | 20 (40 μL) | 200 μL |  |
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This gene encodes a member of the malignant brain tumor (MBT) family of chromatin interacting transcriptional repressors. Members of this family function as methyl-lysine readers, which recognize methylated lysine residues on histone protein tails, and are associated with the repression of gene expression. The encoded protein may regulate hematopoiesis. Homozygous deletion of this gene has been observed in human patients with medulloblastoma. [provided by RefSeq, Oct 2016]
Gene Symbol : L3MBTL3
Gene Name : L3MBTL3, histone methyl-lysine binding protein
Chromosome : CHR 6: 130,018,582-130,141,448
Locus : 6q23.1
Alt. Genes : OPTN
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