The protein encoded by this gene is a zinc finger transcription factor that binds to SP1-like sequences in epsilon- and gamma-globin gene promoters. This binding inhibits cell growth and causes apoptosis. Defects in this gene are a cause of maturity-onset diabetes of the young type 7 (MODY7). Three transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Apr 2010]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| KLF11-20-RE | 20 (40 μL) | 200 μL |  |
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| KLF11-20-OR | 20 (40 μL) | 200 μL |  |
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| KLF11-20-GO | 20 (40 μL) | 200 μL |  |
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| KLF11-20-GR | 20 (40 μL) | 200 μL |  |
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| KLF11-20-AQ | 20 (40 μL) | 200 μL |  |
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The protein encoded by this gene is a zinc finger transcription factor that binds to SP1-like sequences in epsilon- and gamma-globin gene promoters. This binding inhibits cell growth and causes apoptosis. Defects in this gene are a cause of maturity-onset diabetes of the young type 7 (MODY7). Three transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Apr 2010]
Gene Symbol : KLF11
Gene Name : Kruppel like factor 11
Chromosome : CHR 2: 100,435,54-100,548,35
Locus : 2p25.1
Alt. Genes : ENAM
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