Microtubules, polymers of alpha and beta tubulin subunits, form the mitotic spindle of a dividing cell and help to organize membranous organelles during interphase. Katanin is a heterodimer that consists of a 60 kDa ATPase (p60 subunit A 1) and an 80 kDa accessory protein (p80 subunit B 1). The p60 subunit acts to sever and disassemble microtubules, while the p80 subunit targets the enzyme to the centrosome. This gene encodes the p80 subunit. This protein is a member of the AAA family of ATPases. Multiple alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq, Feb 2011]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| KATNA1-20-RE | 20 (40 μL) | 200 μL |  |
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| KATNA1-20-OR | 20 (40 μL) | 200 μL |  |
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| KATNA1-20-GO | 20 (40 μL) | 200 μL |  |
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| KATNA1-20-GR | 20 (40 μL) | 200 μL |  |
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| KATNA1-20-AQ | 20 (40 μL) | 200 μL |  |
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Microtubules, polymers of alpha and beta tubulin subunits, form the mitotic spindle of a dividing cell and help to organize membranous organelles during interphase. Katanin is a heterodimer that consists of a 60 kDa ATPase (p60 subunit A 1) and an 80 kDa accessory protein (p80 subunit B 1). The p60 subunit acts to sever and disassemble microtubules, while the p80 subunit targets the enzyme to the centrosome. This gene encodes the p80 subunit. This protein is a member of the AAA family of ATPases. Multiple alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq, Feb 2011]
Gene Symbol : KATNA1
Gene Name : Katanin catalytic subunit A1
Chromosome : CHR 6: 149,649,017-149,594,872
Locus : 6q25.1
Alt. Genes : KIF20A
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