CBP and p300 are large nuclear proteins that bind to many sequence-specific factors involved in cell growth and/or differentiation, including c-jun and the adenoviral oncoprotein E1A. The protein encoded by this gene associates with p300/CBP. It has in vitro and in vivo binding activity with CBP and p300, and competes with E1A for binding sites in p300/CBP. It has histone acetyl transferase activity with core histones and nucleosome core particles, indicating that this protein plays a direct role in transcriptional regulation. [provided by RefSeq, Jul 2008]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| KAT2B-20-RE | 20 (40 μL) | 200 μL |  |
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| KAT2B-20-OR | 20 (40 μL) | 200 μL |  |
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| KAT2B-20-GO | 20 (40 μL) | 200 μL |  |
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| KAT2B-20-GR | 20 (40 μL) | 200 μL |  |
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| KAT2B-20-AQ | 20 (40 μL) | 200 μL |  |
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CBP and p300 are large nuclear proteins that bind to many sequence-specific factors involved in cell growth and/or differentiation, including c-jun and the adenoviral oncoprotein E1A. The protein encoded by this gene associates with p300/CBP. It has in vitro and in vivo binding activity with CBP and p300, and competes with E1A for binding sites in p300/CBP. It has histone acetyl transferase activity with core histones and nucleosome core particles, indicating that this protein plays a direct role in transcriptional regulation. [provided by RefSeq, Jul 2008]
Gene Symbol : KAT2B
Gene Name : Lysine acetyltransferase 2B
Chromosome : CHR 3: 200,400,31-201,544,03
Locus : 3p24.3
Alt. Genes : HIPK3
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