The protein encoded by this gene is a ubiquitin-like protein that is conjugated to intracellular target proteins upon activation by interferon-alpha and interferon-beta. Several functions have been ascribed to the encoded protein, including chemotactic activity towards neutrophils, direction of ligated target proteins to intermediate filaments, cell-to-cell signaling, and antiviral activity during viral infections. While conjugates of this protein have been found to be noncovalently attached to intermediate filaments, this protein is sometimes secreted. [provided by RefSeq, Dec 2012]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| ISG15-20-RE | 20 (40 μL) | 200 μL |  |
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| ISG15-20-OR | 20 (40 μL) | 200 μL |  |
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| ISG15-20-GO | 20 (40 μL) | 200 μL |  |
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| ISG15-20-GR | 20 (40 μL) | 200 μL |  |
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| ISG15-20-AQ | 20 (40 μL) | 200 μL |  |
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The protein encoded by this gene is a ubiquitin-like protein that is conjugated to intracellular target proteins upon activation by interferon-alpha and interferon-beta. Several functions have been ascribed to the encoded protein, including chemotactic activity towards neutrophils, direction of ligated target proteins to intermediate filaments, cell-to-cell signaling, and antiviral activity during viral infections. While conjugates of this protein have been found to be noncovalently attached to intermediate filaments, this protein is sometimes secreted. [provided by RefSeq, Dec 2012]
Gene Symbol : ISG15
Gene Name : ISG15 ubiquitin-like modifier
Chromosome : CHR 1: 101,346,6-101,453,9
Locus : 1p36.33
Alt. Genes : PDZK1IP1
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