DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. The protein encoded by this gene is a DEAD box protein that is part of a complex that interacts with the C-terminus of RNA polymerase II and is involved in 3' end processing of snRNAs. In addition, this gene is a candidate tumor suppressor and is located in the critical region of loss of heterozygosity (LOH). Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Apr 2015]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| INTS6-20-RE | 20 (40 μL) | 200 μL |  |
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| INTS6-20-OR | 20 (40 μL) | 200 μL |  |
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| INTS6-20-GO | 20 (40 μL) | 200 μL |  |
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| INTS6-20-GR | 20 (40 μL) | 200 μL |  |
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| INTS6-20-AQ | 20 (40 μL) | 200 μL |  |
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DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. The protein encoded by this gene is a DEAD box protein that is part of a complex that interacts with the C-terminus of RNA polymerase II and is involved in 3' end processing of snRNAs. In addition, this gene is a candidate tumor suppressor and is located in the critical region of loss of heterozygosity (LOH). Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Apr 2015]
Gene Symbol : INTS6
Gene Name : Integrator complex subunit 6
Chromosome : CHR 13: 514,532,35-513,531,70
Locus : 13q14.3
Alt. Genes : OPTN
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