The protein encoded by this gene is a member of the interleukin 1 cytokine family. This protein inhibits the activities of interleukin 1, alpha (IL1A) and interleukin 1, beta (IL1B), and modulates a variety of interleukin 1 related immune and inflammatory responses. This gene and five other closely related cytokine genes form a gene cluster spanning approximately 400 kb on chromosome 2. A polymorphism of this gene is reported to be associated with increased risk of osteoporotic fractures and gastric cancer. Several alternatively spliced transcript variants encoding distinct isoforms have been reported. [provided by RefSeq, Jan 2016]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| IL1RN-20-RE | 20 (40 μL) | 200 μL |  |
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| IL1RN-20-OR | 20 (40 μL) | 200 μL |  |
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| IL1RN-20-GO | 20 (40 μL) | 200 μL |  |
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| IL1RN-20-GR | 20 (40 μL) | 200 μL |  |
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| IL1RN-20-AQ | 20 (40 μL) | 200 μL |  |
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The protein encoded by this gene is a member of the interleukin 1 cytokine family. This protein inhibits the activities of interleukin 1, alpha (IL1A) and interleukin 1, beta (IL1B), and modulates a variety of interleukin 1 related immune and inflammatory responses. This gene and five other closely related cytokine genes form a gene cluster spanning approximately 400 kb on chromosome 2. A polymorphism of this gene is reported to be associated with increased risk of osteoporotic fractures and gastric cancer. Several alternatively spliced transcript variants encoding distinct isoforms have been reported. [provided by RefSeq, Jan 2016]
Gene Symbol : IL1RN
Gene Name : Interleukin 1 receptor antagonist
Chromosome : CHR 2: 113,099,364-113,134,015
Locus : 2q14.1
Alt. Genes : CHST4
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