The protein encoded by this gene is a cytokine receptor. This receptor specifically binds to IL17B and IL17E, but does not bind to IL17 and IL17C. This receptor has been shown to mediate the activation of NF-kappaB and the production of IL8 induced by IL17E. The expression of the rat counterpart of this gene was found to be significantly up-regulated during intestinal inflammation, which suggested the immunoregulatory activity of this receptor. [provided by RefSeq, Jul 2008]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| IL17RB-20-RE | 20 (40 μL) | 200 μL |  |
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| IL17RB-20-OR | 20 (40 μL) | 200 μL |  |
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| IL17RB-20-GO | 20 (40 μL) | 200 μL |  |
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| IL17RB-20-GR | 20 (40 μL) | 200 μL |  |
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| IL17RB-20-AQ | 20 (40 μL) | 200 μL |  |
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The protein encoded by this gene is a cytokine receptor. This receptor specifically binds to IL17B and IL17E, but does not bind to IL17 and IL17C. This receptor has been shown to mediate the activation of NF-kappaB and the production of IL8 induced by IL17E. The expression of the rat counterpart of this gene was found to be significantly up-regulated during intestinal inflammation, which suggested the immunoregulatory activity of this receptor. [provided by RefSeq, Jul 2008]
Gene Symbol : IL17RB
Gene Name : Interleukin 17 receptor B
Chromosome : CHR 3: 538,464,93-538,665,25
Locus : 3p21.1
Alt. Genes : PLXNC1
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