This gene encodes a member of the insulin-like growth factor (IGF)-binding protein (IGFBP) family. IGFBPs bind IGFs with high affinity, and regulate IGF availability in body fluids and tissues and modulate IGF binding to its receptors. This protein binds IGF-I and IGF-II with relatively low affinity, and belongs to a subfamily of low-affinity IGFBPs. It also stimulates prostacyclin production and cell adhesion. Alternatively spliced transcript variants encoding different isoforms have been described for this gene, and one variant has been associated with retinal arterial macroaneurysm (PMID:21835307). [provided by RefSeq, Dec 2011]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| IGFBP7-20-RE | 20 (40 μL) | 200 μL |  |
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| IGFBP7-20-OR | 20 (40 μL) | 200 μL |  |
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| IGFBP7-20-GO | 20 (40 μL) | 200 μL |  |
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| IGFBP7-20-GR | 20 (40 μL) | 200 μL |  |
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| IGFBP7-20-AQ | 20 (40 μL) | 200 μL |  |
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This gene encodes a member of the insulin-like growth factor (IGF)-binding protein (IGFBP) family. IGFBPs bind IGFs with high affinity, and regulate IGF availability in body fluids and tissues and modulate IGF binding to its receptors. This protein binds IGF-I and IGF-II with relatively low affinity, and belongs to a subfamily of low-affinity IGFBPs. It also stimulates prostacyclin production and cell adhesion. Alternatively spliced transcript variants encoding different isoforms have been described for this gene, and one variant has been associated with retinal arterial macroaneurysm (PMID:21835307). [provided by RefSeq, Dec 2011]
Gene Symbol : IGFBP7
Gene Name : Insulin like growth factor binding protein 7
Chromosome : CHR 4: 571,103,84-570,310,70
Locus : 4q12
Alt. Genes : YAF2
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