The protein encoded by this gene is one of six similar proteins that bind insulin-like growth factors I and II (IGF-I and IGF-II). The encoded protein can be secreted into the bloodstream, where it binds IGF-I and IGF-II with high affinity, or it can remain intracellular, interacting with many different ligands. High expression levels of this protein promote the growth of several types of tumors and may be predictive of the chances of recovery of the patient. Several transcript variants, one encoding a secreted isoform and the others encoding nonsecreted isoforms, have been found for this gene. [provided by RefSeq, Sep 2015]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| IGFBP2-20-RE | 20 (40 μL) | 200 μL |  |
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| IGFBP2-20-OR | 20 (40 μL) | 200 μL |  |
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| IGFBP2-20-GO | 20 (40 μL) | 200 μL |  |
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| IGFBP2-20-GR | 20 (40 μL) | 200 μL |  |
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| IGFBP2-20-AQ | 20 (40 μL) | 200 μL |  |
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The protein encoded by this gene is one of six similar proteins that bind insulin-like growth factors I and II (IGF-I and IGF-II). The encoded protein can be secreted into the bloodstream, where it binds IGF-I and IGF-II with high affinity, or it can remain intracellular, interacting with many different ligands. High expression levels of this protein promote the growth of several types of tumors and may be predictive of the chances of recovery of the patient. Several transcript variants, one encoding a secreted isoform and the others encoding nonsecreted isoforms, have been found for this gene. [provided by RefSeq, Sep 2015]
Gene Symbol : IGFBP2
Gene Name : Insulin like growth factor binding protein 2
Chromosome : CHR 2: 216,632,827-216,664,435
Locus : 2q35
Alt. Genes : OPTN
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