This gene encodes a member of the insulin family of polypeptide growth factors, which are involved in development and growth. It is an imprinted gene, expressed only from the paternal allele, and epigenetic changes at this locus are associated with Wilms tumour, Beckwith-Wiedemann syndrome, rhabdomyosarcoma, and Silver-Russell syndrome. A read-through INS-IGF2 gene exists, whose 5' region overlaps the INS gene and the 3' region overlaps this gene. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2010]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| IGF2-20-RE | 20 (40 μL) | 200 μL |  |
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| IGF2-20-OR | 20 (40 μL) | 200 μL |  |
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| IGF2-20-GO | 20 (40 μL) | 200 μL |  |
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| IGF2-20-GR | 20 (40 μL) | 200 μL |  |
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| IGF2-20-AQ | 20 (40 μL) | 200 μL |  |
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This gene encodes a member of the insulin family of polypeptide growth factors, which are involved in development and growth. It is an imprinted gene, expressed only from the paternal allele, and epigenetic changes at this locus are associated with Wilms tumour, Beckwith-Wiedemann syndrome, rhabdomyosarcoma, and Silver-Russell syndrome. A read-through INS-IGF2 gene exists, whose 5' region overlaps the INS gene and the 3' region overlaps this gene. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2010]
Gene Symbol : IGF2
Gene Name : Insulin like growth factor 2
Chromosome : CHR 11: 214,960,2-212,911,1
Locus : 11p15.5
Alt. Genes : PREB
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