This gene encodes a member of the homeodomain-containing superfamily of transcription factors. The protein binds to DNA as either a homodimer, or a heterodimer with the related protein hepatocyte nuclear factor 1-alpha. The gene has been shown to function in nephron development, and regulates development of the embryonic pancreas. Mutations in this gene result in renal cysts and diabetes syndrome and noninsulin-dependent diabetes mellitus, and expression of this gene is altered in some types of cancer. Multiple transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Sep 2009]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| HNF1B-20-RE | 20 (40 μL) | 200 μL |  |
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| HNF1B-20-OR | 20 (40 μL) | 200 μL |  |
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| HNF1B-20-GO | 20 (40 μL) | 200 μL |  |
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| HNF1B-20-GR | 20 (40 μL) | 200 μL |  |
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| HNF1B-20-AQ | 20 (40 μL) | 200 μL |  |
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This gene encodes a member of the homeodomain-containing superfamily of transcription factors. The protein binds to DNA as either a homodimer, or a heterodimer with the related protein hepatocyte nuclear factor 1-alpha. The gene has been shown to function in nephron development, and regulates development of the embryonic pancreas. Mutations in this gene result in renal cysts and diabetes syndrome and noninsulin-dependent diabetes mellitus, and expression of this gene is altered in some types of cancer. Multiple transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Sep 2009]
Gene Symbol : HNF1B
Gene Name : HNF1 homeobox B
Chromosome : CHR 17: 377,450,77-376,864,30
Locus : 17q12
Alt. Genes : CELA3A
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